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These cells, found in tissues such as the skin, boost immune responses by interacting with the body’s T cells in various ways.17 18 The way TA-1 can modulate dendritic cell function may lead to enhanced Th1 and Treg cells (two immune system T cells with opposing roles that both affect inflammation), ultimately balancing the body’s inflammatory response.4 7 19 As noted by the authors of a 2018 review, “Th17 cells cause autoimmunity and inflammation, whereas Treg cells inhibit these phenomena and maintain immune homeostasis.” (Th17 cells are a precursor to Th1 cells.)19 Cancer In the 2024 review we mentioned earlier, the researchers state that TA-1 is “being explored as an immunotherapeutic agent” either alone or with chemotherapy/radiotherapy for various types of cancers, such as melanoma, hepatocellular carcinoma, and lung cancer

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10.1016/0378-4274(95)03532-x Toxicol